Hello,
Well..It depends on many factors like
01. The way the table is designed - with appropriate datatypes,Appropriate indexes,Partitioned or non partitioned
02. The health of Indexes - should not be heavily fragmented and statistics are uptodate
03. The data access mechanism - data should be accessed by writing the most optimzed code and applying the appropriate locks and
isolation levels with relevance to the type operation being performed ie.select/update/insert/delete
And also you can check the actual Execution plan and statistics for the queries pointing to this table and can be fine tuned if they are not responding with in a reasonable time.
Thanks,
Narchand